University of Würzburg


General description
The UWUE partners are located at the Rudolf Virchow Center and the Institute of Pharmacology, with both being directed by Martin J. Lohse. Together these organisations comprise of almost 200 researchers and staff, and are funded as a national centre of excellence by the German Research Foundation (DFG). The research groups study target proteins, with a focus on GPCRs, using methods of pharmacology, biochemistry, mass spectrometry, structural biology and optical microscopy. Doctoral researchers will be integrated into the Graduate School of Life Sciences, which is also funded by the DFG as a programme of excellence.

Key research facilities, infrastructures and equipment
Over 25 years of expertise in GPCR pharmacology including pioneering development of fluorescence techniques, research on regulatory proteins and GPCR fluorescence imaging studies and their signalling pathways. We have at our disposal numerous optical microscopes, including high resolution STED-, several 2-photon-, FLIM-, FCS-, TIRF-microscopes, a range of FRET microscopes and high-throughput systems, plus X-ray and EM-structural biology, mass spectrometry and SPF mouse facilities.

Project members 

  •  Prof. Martin Lohse
  • Prof. Carsten Hoffmann

Follow us on

Great way to finish the week off with some #FCS measurements of CXCR4-expressing HEK cells at @UoNLifeSci 🔬 #FluorescenceFriday

Hello everyone!
I am Noemi Karsai and I’m the next in our #ESR introduction series. I’m #ESR11 and I’m originally from Hungary, currently doing my PhD at @UoNLifeSci @COMPARE_UoBUoN, UK.

The transatlantic ECI GPCR symposium #ECIGPCR is about to start, we are ready!! Thanks to the organizers for their excellent job gathering almost 500 people across the globe! @cyclic_Andreas @NicoleAPerry1 @BenderSci @DesislavaNeshe1

Hello 🙂
I am here to continue the series in which all #ESRs are presenting themselves. I am Viviana Marolda and I am in my first year of PhD. I am #ESR13, originally from Italy, and currently, I am working as a PhD student in @CBMSO_CSIC_UAM, at Universidad Autonoma de Madrid.

Hey twitter!
I am @DehanComez. I am taking over the Oncornet account for a while to start a series of all #ESRs writing about themselves and their projects. I am #ESR5, originally from Turkey and right now I am working as a PhD student in @COMPARE_UoBUoN , @UniofNottingham , UK.

New review on #gpcr structural dynamics out in COSB. Great teamwork with the @JanaSelent group. Thanks to @Lundbeckfonden and @novonordiskfond

ONCORNET2.0 is the successor to #ONCORNET. You can see some of the work of ESRs from the first ONCORNET in this special issue of @MolPharmJournal from 2019, with reviews on #CXCR4 and #ACKR3 structure and function:

Hi everyone – we’re on Twitter! ONCORNET2.0 is a #MarieCurie ITN of 16 ESRs across Europe studying #chemokine #GPCRs #CXCR4 and #ACKR3 in cancer. Our projects cover molecular dynamics, medchem, #pharmacology through to translational work. Follow us for updates from our ESRs!

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Contact details

Please contact us at:

ONCORNET Coordinator
VU University Amsterdam
The Netherlands